Nuclear Magnetic Resonance and Nucleic Acids by Thomas L. James (Eds.)

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By Thomas L. James (Eds.)

The severely acclaimed laboratory common for 40 years, Methods in Enzymology is without doubt one of the so much hugely revered courses within the box of biochemistry. when you consider that 1955, every one quantity has been eagerlyawaited, often consulted, and praised via researchers and reviewers alike. greater than 250 volumes were released (all of them nonetheless in print) and masses of the cloth is correct even today--truly an important e-book for researchers in all fields of lifestyles sciences

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M. Egan, and T. L. James, J. Mol, Biol. 227, 510 (1992); (5) K. Weisz, R. H. Sharer, W. Egan, and T. L. James, Biochemistry 33, 354 (1994); (6) K. D. Bishop, F. Blocker, W. Egan, and T. L. James, Biochemistry 33, 427 (1994); (7) A. Mujeeb, S. M. Kerwin, W. Egan, G. L. Kenyon, and T. L. James, Biochemistry 31, 9325 (1992); (8) M. Tonelli and T. L. James, unpublished results (1995); (9) C, Gonzalez, W. Stec, A. Kobylanska, R. I. Hogrefe, M. Reynolds, and T. L. James, Biochemistry 33, 11062 (1994).

60. 60. g B ~ g Ps Ps Fie. 1. (continued) ~ g fs [1] ACCURATE SOLUTION STRUCTURES 21 Om 4 0 ° JHI'2' J H1 '2" g0. 90. 80. 80, 70. 70. fs 60. U P, P, JH2'3' JH2"3' fs 60. -B 90, 90. 80. 80. 70. 70. 60. 60. fs - - C _ , . . . . . . , . . o- . . . P, . . . . . . Ps FiG. 1. (continued) fs 22 DNA AND RNA STRUCTURE [11 SPHINX, 63which calculates the corresponding energy transition for various COSY-type experiments. , digital resolution, apodization functions and truncation effects, and the effective linewidth of the nuclei involved).

Mujeeb, S. M. Kerwin, W. Egan, G. L. Kenyon, and T. L. James, Biochemistry 31, 9325 (1992); (8) M. Tonelli and T. L. James, unpublished results (1995); (9) C, Gonzalez, W. Stec, A. Kobylanska, R. I. Hogrefe, M. Reynolds, and T. L. James, Biochemistry 33, 11062 (1994). type of COSY technique, where spectra are recorded for individual peaks, results in much higher digital resolution and ultimately in narrower error margins for the coupling constants. Despite the improved precision, slightly different results were obtained for an individual coupling constant when fitting different peaks.

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