
By Chad A. Mirkin, Christof M. Niemeyer
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Example text
K. (1985) The monensin-mediated transport of sodium ions through phospholipid bilayers studied by 23 Na-NMR spectroscopy. Biochim. Biophys. Acta 817, 313–317. Espı´nola, C. , Martı´n, J. D. (2000) Synthetic flux-promoting polyether models: cation flux dependence on polyoxyethylene chain length. Isr. J. Chem. 40, 279–288. , Gokel, G. W. (1995) Synthetic models for transmembrane channels: structural variations that alter cation flux. J. Am. Chem. Soc. 117, 7665– 7679. Pregel, M. -M. (1992) Towards artificial ion channels: transport of alkali metal ions across liposomal membranes by ‘‘bouquet’’ molecules.
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A full discussion of these exciting investigations is beyond the scope of this chapter, but can be found in reports and reviews provided by Yeates’s group [4]. 4 Summary: Pros and Cons of Peptide-Based Assembly of Nanofibers The preceding sections of this chapter have introduced the concepts and examples of peptide-based, self-assembling fibers. We have focused on constructions using a-helically structured peptides, although fibers have been generated by many others using b-amyloid-like structures, collagen triple helices and larger natural protein units.