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By Ted Lister; Colin Osborne; Maria Pack
This source demonstrates how a mix of recent concepts is used to make sure that horseracing is either reasonable and forestalls abuse of the horses concerned, This source demonstrates how a mixture of recent strategies is used to make sure that horseracing is either reasonable and stops abuse of the horses concerned. in line with the paintings of the Horseracing Forensic Laboratory (HFL) positioned close to Newmarket within the united kingdom, the ebook includes 5 sections of scholar fabric. First, an outline of the paintings of HFL is gifted, by means of sections on immunoassay, metabolism and chromatography. lecturers' notes also are incorporated. Following the explanatory textual content are questions, which support with figuring out and in addition illustrate real-life purposes of the chemical innovations encountered in school. Chemistry on the Races is designed commonly for a long time 16+, yet a few fabric is additionally integrated for more youthful scholars. it really is a useful source for lecturers, permitting them to illustrate an up to date and engaging context for his or her paintings learn more... content material: advent -- academics' notes and solutions -- Chemistry on the races -- Detecting medications in horse urine by way of immunoassay -- Drug metabolism -- opting for medicinal drugs in horse urine by way of fuel Chromatography -- Mass Spectrometry (GCMS) -- trying out for medicines in racehorses utilizing chromatography. summary: This source demonstrates how a mixture of recent options is used to make sure that horseracing is either reasonable and forestalls abuse of the horses concerned, This source demonstrates how a mixture of recent concepts is used to make sure that horseracing is either reasonable and forestalls abuse of the horses concerned. in response to the paintings of the Horseracing Forensic Laboratory (HFL) situated close to Newmarket within the united kingdom, the booklet contains 5 sections of pupil fabric. First, an summary of the paintings of HFL is gifted, by means of sections on immunoassay, metabolism and chromatography. academics' notes also are integrated. Following the explanatory textual content are questions, which support with realizing and in addition illustrate real-life purposes of the chemical suggestions encountered in school. Chemistry on the Races is designed typically for a while 16+, yet a few fabric is additionally incorporated for more youthful scholars. it truly is a useful source for academics, permitting them to illustrate an updated and fascinating context for his or her paintings
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Extra resources for Chemistry at the races : The work of the horseracing forensic laboratory
Example text
4 6 . Suggest how the HFL could prove that a particular compound is a metabolite of a drug that could be given to a horse. Explain in full the steps that would have to be carried out. 47. What other sports do you think could use this type of drug testing? 48. Human athletes sometimes take performance-enhancing drugs. What other reasons are there, apart from those in the passage, to test animal athletes?
The stationary phase is usually a solid. The mobile phase may be either a liquid or a gas. Mixtures separate as the mobile phase moves through the stationary phase (like water spreads through blotting paper) dragging the components (bits) of the mixture with it. Separation happens because some chemicals are more attracted to the paper than the alcohol and tend to lag behind. Others are more attracted to the alcohol than the paper and so move faster. So in Figure 1, the blue dye i s more attracted to the alcohol than the red dye and so moves further in the same time.
What types of reaction are a, b, c and d? aceprornazine PH3 iH3 a lc iH3 d OH Figure 8 Metabolism of acepromazine Q7. Which other functional groups of the acepromazine molecule might be susceptible to metabolic change by phase I reactions? Phase I1 Reactions The product of the reaction of glucuronic acid with acepromazine metabolite i s shown in Figure 9. This product is termed a glucuronide. e0yyyJ / HO / Figure 9 The glucuronide of acepromazine metabolite Q8. a) b) How will the formation of the glucuronide affect the water-solubility of the metabolite?