Toxicology by Gary D. Osweiler

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By Gary D. Osweiler

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This was not at all satisfactory. If put under pressure to repeat Pouchet’s experiment, Pasteur would presumably have found similar results and would have had to investigate the hay infusions further. The problem was properly solved 14 years later after the Englishman Charlton Bastian suggested that boiled urine would support the spontaneous generation of life. Pasteur was provoked to refute this and, after much effort, he and his colleagues found an explanation that applied to both Pouchet’s and Bastian’s experiments: some bacteria were very resistant to heat, and could not be killed by heating to 100°C.

This was not at all satisfactory. If put under pressure to repeat Pouchet’s experiment, Pasteur would presumably have found similar results and would have had to investigate the hay infusions further. The problem was properly solved 14 years later after the Englishman Charlton Bastian suggested that boiled urine would support the spontaneous generation of life. Pasteur was provoked to refute this and, after much effort, he and his colleagues found an explanation that applied to both Pouchet’s and Bastian’s experiments: some bacteria were very resistant to heat, and could not be killed by heating to 100°C.

He was a serious student,1 fond of reading and talking of crystals and mathematics, and reading philosophy. Indeed he showed a real talent as a painter, as some of the pictures on the walls of the Pasteur Museum demonstrate. At the École Normale, Pasteur’s progress was creditable, without being viewed as outstanding. By 1847 he had obtained his doctorate degree with dissertations in chemistry and physics—much to the pride of his parents. By this time he had exceeded the ambitions that they had for their only son.

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