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By Hans Hedrich
Between animals utilized in examine, educating and trying out, mice at the moment are widely known because the most vital version for human ailments and issues. They include nearly all of all experimental mammals and have a tendency to be the version of selection used for learn into many diseases/disorders together with melanoma, center affliction, bronchial asthma, Alzheimer's, Down syndrome, deafness, osteoporosis, weight problems, diabetes or even psychological future health learn. also the laboratory mouse maintains to play a greatly publicized very important function within the human genome project.One of the main time-consuming actions in examine laboratories is asking up info particular to the species or pressure of animal getting used. This booklet, a part of the hugely profitable guide of Experimental Animals sequence, permits the person easy access to any focal point at the mouse as an experimental version. * Edited through Hans Hedrich, Hannover scientific institution* finished reference resource written by means of overseas specialists* Well-illustrated with top of the range precise photographs* Two-color, elementary layout mixed with colour plate sections
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Extra resources for The Laboratory Mouse (Handbook of Experimental Animals)
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1905). Arch. ZooL Exp. Gen. 4, 123-132. T. (1999). Lab. Anim. (Millenium Issue) 28, 2-5. T. H. (1978). Cytogenet. Cell Genet. 22, 552-557. L. N. (1990). In Genetic Maps, 5th edn (ed. J. O'Brien), pp. 14. Cold Spring Harbor Laborarory Press, Cold Spring Harbor. K. (1978). In Origins of Inbred Mice, Proceedings of a Workshop, Bethesda, MD, February 1978 (ed. C. Morse, III), pp. 99-102. Academic Press, New York. C. S. (1994). Nat. Genet. 7, 220-245. , Maeda, N. and Smithies, O. (1988). Proc. Natl.
In Origins of Inbred Mice, Proceedings of a Workshop, Bethesda, MD, February 1978 (ed. C. Morse, III), pp. 3-21. Academic Press, New York. , III. (1985). Immunogenetics21, 109-116. Mouse Genome Informatics (MGI), The Jackson Laboratory, Bar Harbor, Maine. (2003). http:/lwww. P. (1994). Science 264, 1329-1333. , Matin, A. S. (2000). Nat. Genet. 24, 221-225. H. A. (1984). Proc. Natl. Acad. Sci. A. 81,814-818. Nagy, A. (2000). Genesis26, 99-109. , Sandmeyer, S. and Plasterk, R. (2003). Nat. Genet.
A selected list of electronic resources available to gain entry into the broad areas of mouse genetics and biomedical research is provided in Chapter 3 on Strains, Stocks, and Mutant Mice. "T' O r" ~1 O The future ITI The future of the mouse in genome analysis and as a model organism seems virtually unlimited. Whole genome sequence and gene prediction programs make it quite feasible to knock out or genetically modify every mouse gene. Almost certainly, ES cells will play a key role in future mouse genomics because they can be manipulated in culture.