Fluconazole: Pharmacology, Clinical Uses and Health Effects by Santiago Herrera, Joaquin Acosta

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By Santiago Herrera, Joaquin Acosta

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Invasive Candidiasis 2013 [july 4 2013]. gov/fungal/ candidiasis/invasive/. Sobel JD, Fisher JF, Kauffman CA, Newman CA. Candida urinary tract infections--epidemiology. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. 2011;52 Suppl 6:S433-6. Bagshaw SM, Laupland KB. Epidemiology of intensive care unitacquired urinary tract infections. Current opinion in infectious diseases. 2006;19(1):67-71. Shoham S, Marwaha S. Invasive fungal infections in the ICU.

2001). , 2012). Potential isolates from turtles with fungal pneumonia include Aspergillus, Candida, Mucor, Geotrichum, Penicillium, Cladosporium, Rhizopus, Beauveria, Sporotrichum, Basidiobolus, and Paecilomyces spp. (Norton, 2005). The reason for the use of fluconazole in these cases may be related more to administration factors than to an ideal spectrum of action for potential pathogens.

In: Brunton L, Chabner B, Knollmann B, editors. GOODMAN & GILMAN As Bases Farmacológicas da Terapêutica. 12a ed. Porto Alegre: Editora McGrawHill, AMGH Editora, Ltda; 2012. Louie A, Drusano GL, Banerjee P, Liu QF, Liu W, Kaw P, et al. Pharmacodynamics of fluconazole in a murine model of systemic candidiasis. Antimicrobial agents and chemotherapy. 1998;42(5):11059. Aoyama T, Hirata K, Hirata R, Yamazaki H, Yamamoto Y, Hayashi H, et al. Population pharmacokinetics of fluconazole after administration of fosfluconazole and fluconazole in critically ill patients.

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